The Centers for Medicare & Medicaid Services (CMS) is announcing a free on-line training course in infection prevention and control for nursing home staff in the long-term care setting developed with the Centers for Disease Control and Prevention (CDC). The course information covers core activities for an infection prevention and control program, with a detailed explanation of recommended practices to prevent pathogen transmission and reduce healthcare-associated infections and antibiotic resistance in nursing homes. Course overview and materials are available on the CDC’s TRAIN website (https://www.train.org/cdctrain/training_plan/3814).